About this item
The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).
The 11B11 antibody is widely used for detection of intracellular levels of IL-4 protein by flow cytometry, as well as for analysis of soluble cytokine as measured by ELISA, and in functional assays to neutralization cytokine-receptor interactions. Please choose the appropriate format for each application.
Type: Primary
Antigen: IL4 (interleukin 4)
Clonality: monoclonal
Clone: 11B11
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Rat
Isotype: IgG1 Kappa
Reactivity: Mouse
Specifications
- Catalog No:
- 20-7041-U100
- 20-7041-U025
- Antigen symbol:
- IL4
- IL4
- Antigen name:
- Interleukin 4
- Interleukin 4
- Antigen synonyms:
- BCGF-1|B-cell stimulatory factor 1|IL-4|BCGF1|BSF1|BSF-1|Interleukin-4
- BCGF-1|B-cell stimulatory factor 1|IL-4|BCGF1|BSF1|BSF-1|Interleukin-4
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- APC (Allophycocyanin)
- APC (Allophycocyanin)
- Clone:
- 11B11
- 11B11
- Reactivity:
- Mouse
- Mouse
- Host:
- Rat
- Rat
- Gene ID:
- 16189
- 16189
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ELISA:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Flow cytometry:
- Yes
- Yes
- Neutralisation:
- Yes
- Yes
- Cross adsorption:
- none
- none
- Storage temperature:
- Cool
- Cool
- Shipping temperature:
- 4 °C
- 4 °C
- Tested applications:
- Flow Cytometry
- Flow Cytometry
Specifications
Product Information
- Catalog #Supplier #PkAvailabilityPrice
- Supplier Article Number: 20-7041-U100Local Article Number: TNBO20-7041-U100Specifications:
More
Specifications
Antigen symbolIL4Antigen nameInterleukin 4Environmentally PreferableAntigen synonymsBCGF-1|B-cell stimulatory factor 1|IL-4|BCGF1|BSF1|BSF-1|Interleukin-4Antibody typePrimaryClonalityMonoclonalConjugationAPC (Allophycocyanin)Clone11B11ReactivityMouseHostRatGene ID16189IsotypeIgG1 kappaELISAYesImmunoChemistryYesImmunoFluorescenceYesFlow cytometryYesNeutralisationYesCross adsorptionnoneStorage temperatureCoolShipping temperature4 °CTested applicationsFlow Cytometry - Supplier Article Number: 20-7041-U025Local Article Number: TNBO20-7041-U025Specifications:
More
Specifications
Antigen symbolIL4Antigen nameInterleukin 4Environmentally PreferableAntigen synonymsBCGF-1|B-cell stimulatory factor 1|IL-4|BCGF1|BSF1|BSF-1|Interleukin-4Antibody typePrimaryClonalityMonoclonalConjugationAPC (Allophycocyanin)Clone11B11ReactivityMouseHostRatGene ID16189IsotypeIgG1 kappaELISAYesImmunoChemistryYesImmunoFluorescenceYesFlow cytometryYesNeutralisationYesCross adsorptionnoneStorage temperatureCoolShipping temperature4 °CTested applicationsFlow Cytometry