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Anti-TACR1 Rabbit Polyclonal Antibody

Leverancier: Thermo Scientific
The target sequence has 92% sequence homology with canine. The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma. Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Type: Primary
Antigen: TACR1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Guinea Pig, Human, Mouse, Rat



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Maat VPE VWR catalogus nummer Hoeveelheid
100 µL 100 µl PIEAPA116713 Blocked
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Specificaties

Antigen symbol TACR1
Antigen name Substance P Receptor
Reactivity Mouse, Human, Rat, Guinea Pig
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Antigen synonyms TAC1R, Substance P receptor, NK1R, TACR1, NK1 receptor, Tachykinin receptor 1, SPR
Gene ID 24807, 100135626, 6869, 21336
Formaat whole serum
Immunogen Raised against a synthetic peptide at the c-terminus of rat NK-1 conjugated to bovine thyroglobulin.
Form Liquid
Opslagbuffer whole serum, no preservative
Opslagtemperatuur -20° C, Avoid Freeze/Thaw Cycles
Shipping Temperature Ice
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