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Anti-SLC7A11 Rabbit Polyclonal Antibody

Leverancier: Thermo Scientific
This antibody is predicted to react with mouse and canine based on 100% sequence homology. This antibody has 94% sequence homology with rat. Suggested positive control: human stomach protein, stomach tissue lysate. Mammalian amino acid transport systems consist of a large variety of transporters. The amino acid transporter, cystine/glutamic acid transporter xCT, for system xc has been proposed to be responsible for the cystine transport through the plasma membrane. System xc mediates an amino acid exchange and prefers cystine and glutamate as its substrates. The transporter designated as xCT requires 4F2 heavy chain (4F2hc:CD98) for its functional expression, and belongs to the family of amino acid transporters that associates with the type II membrane glycoproteins such as 4F2hc. In brain, it has been proposed that system xc is up-regulated in glial cells upon oxidative stress and plays an essential roles to protect neurons against oxidative stress. Recent studies have implicated xCT as a gateway that Kaposi's sarcoma herpesvirus (KSHV) uses to enter cells.

Type: Primary
Antigen: SLC7A11
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human



 

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Maat VPE VWR catalogus nummer Hoeveelheid
100 µL 100 µl PIEAPA116775 Blocked
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Specificaties

Antigen symbol SLC7A11
Antigen name Solute Carrier Family 7 Member 11
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ImmunoFluorescence Yes
Antigen synonyms Amino acid transport system xc-xCT, Calcium channel blocker resistance protein CCBR1, Cysteine/glutamate transporter
Gene ID 23657
Concentratie 1 mg/ml
Immunogen A synthetic peptide made to a region within the N-terminus of the murine XCT protein sequence (between residues 1-50).
Purification Antigen affinity chromatography
Form Liquid
Opslagbuffer tris glycine, 0.15M NaCl, 0.05% sodium azide
Opslagtemperatuur Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping temperature Ice

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