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Anti-ABCA1 Rabbit Polyclonal Antibody

Leverancier: Thermo Scientific
ABCA1 is known to aggregate. DO NOT BOIL SAMPLES. Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

Type: Primary
Antigen: ABCA1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Hamster, Canine, Chicken, Human, Mustelid, Rat, Porcine, Mouse




 

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Specificaties

Antigen symbol ABCA1
Antigen name ATP Binding Cassette, sub-family A, member 1
Reactivity Hamster, Porcine, Mouse, Chicken, Human, Dog, Rat, Mustelid
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Gel shift Yes
Flow cytometry Yes
ChIP Yes
Antigen synonyms ATP-binding Cassette Transporter 1, ATP-binding Cassette 1, ABC-1, ABC Transporter 1, Cholesterol Efflux Regulatory Protein, CERP, ABC 1, ABC1
Gene ID 313210, 19, 11303
Concentratie 1 mg/ml
Immunogen Partial peptide sequence corresponding to a sequence between residues 1100-1300 of human ABCA1.
Purification Antigen affinity chromatography
Form Liquid
Opslagbuffer PBS, 0.05% sodium azide
Opslagtemperatuur 4° C, do not freeze
Shipping temperature Ice

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