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Anti-NOD2 Rabbit Polyclonal Antibody

Leverancier: Thermo Scientific
This antibody is predicted to react with monkey based on 100% sequence homology. NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease.

Type: Primary
Antigen: NOD2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human



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Maat VPE VWR catalogus nummer Hoeveelheid
100 µL 100 µl PIEAPA116859 Blocked
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Specificaties

Antigen symbol NOD2
Antigen name Nucleotide binding oligomerization domain containing 2
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Antigen synonyms IBD1, Inflammatory Bowel disease protein 1, NOD 2, CARD15, Caspase recruitment domain protein 15, NOD-2
Gene ID 64127
Concentratie 0.87 mg/ml
Immunogen A synthetic peptide made to the C-terminal region of the human NOD2 protein sequence (between residues 1,000-1,040).
Purification Antigen affinity chromatography
Form Liquid
Opslagbuffer tris glycine, 150mM NaCl, 0.05% sodium azide
Opslagtemperatuur Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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