Anti-NOD2 Rabbit Polyclonal Antibody

Leverancier: Thermo Fisher Scientific
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PIEAPA116859
Anti-NOD2 Rabbit Polyclonal Antibody
Antilichamen
This antibody is predicted to react with monkey based on 100% sequence homology. NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease.

Type: Primary
Antigen: NOD2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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