About this item
Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. FGF-basic is a critical component for embryonic stem cell culture systems and is necessary for maintaining cells in an undifferentiated state. Degredation of the full length FGF-basic N-terminus results in a truncated FGF-basic 147aa protein, when the protein is isolated from biological sources. The N-terminus extensions influence the localization of FGF-basic within the cell, but do not affect the biological activity of FGF-basic. Therefore, there are no detectable differences in biological activity between the full length FGF-basic 154aa and the truncated FGF-basic 147aa recombinant proteins.
- High Quality
- Low Endotoxin
- Affordable
A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
Specifications
- Conjugatie:Onconjugeerd
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Bron:E. coli
- Species:Human
- Storage conditions:–20 °C
- Endotoxinegehalte:Endotoxin LAL (EU/µg) ≤0,1
- Biologische activiteiten:Bioactivity assay: NR6R-3T3 cell proliferation, ED50 ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
- Gen-ID:P09038
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Endotoxinevrij:N
- Dragervrij:Y
- Protease-free:N
- Diervrij:N
- Protein synonyms:Prostatropin|HBGF-2|FGF2
- Protein/peptide name:FGF-basic 147
- Zuiverheid:≥95%
- Moleculair gewicht:16,5 kDa
- Sequentie:MPALPEDGGS GAFPPGHFKD PKRLYCKNGG FFLRIHPDGR VDGVREKSDP HIKLQLQAEE RGVVSIKGVC ANRYLAMKED GRLLASKCVT DECFFFERLE SNNYNTYRSR KYTSWYVALK RTGQYKLGSK TGPGQKAILF LPMSAKS
- Formulering:10 mM sodium phosphate, 75 mM sodium chloride, pH 7,5
- Vrij van nucleasen:N
- Nr:RUO
- Shipping temperature:RT
- Tested applications:Bioassay
Specifications
Product Information
- Catalog #Supplier #VerpakkingVPEAvailabilityPrice
- Supplier Article Number: 100-28-10UGLocal Article Number: SHBT100-28-10UG
- Supplier Article Number: 100-28-50UGLocal Article Number: SHBT100-28-50UG
- Supplier Article Number: 100-28-100UGLocal Article Number: SHBT100-28-100UG
- Supplier Article Number: 100-28-500UGLocal Article Number: SHBT100-28-500UG
- Supplier Article Number: 100-28-1MGLocal Article Number: SHBT100-28-1MG