5194 Results for: "Methotrexate+hydrate"
Methotrexate hydrate 99%
Supplier: Thermo Fisher Scientific
Methotrexate hydrate 99%
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Methotrexate hydrate ≥98.0% (by HPLC, titration analysis)
Supplier: TCI
Methotrexate hydrate ≥98.0% (by HPLC, titration analysis)
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Methotrexate
Supplier: Apollo Scientific
An antineoplastic agent which acts as an antimetaboliteof folic acid.
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Methotrexate ≥98%, orange powder USP
Supplier: MP Biomedicals
Folic Acid antagonist; structurally similar to folic acid. Methotrexate is a mixture of 4-amino-10-methylfolic acid and closely related compounds.
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Sodium methotrexate 98.5%
Supplier: Thermo Fisher Scientific
Sodium methotrexate 98.5%
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Methotrexate, yellow powder Ph. Eur., USP
Supplier: MP Biomedicals
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
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Fluorescein methotrexate triammonium salt ≥95% (by HPLC) fluorescent dye
Supplier: Biotium
Fluorescein methotrexate is useful for studying anti-metabolite resistance and spontaneous gene amplification. The dye is actively taken up by cells and binds to dihydrofolate reductase (DHFR) quantitatively.
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4-Fluorophenylglyoxal hydrate, hydrate 98% (dry weight)
Supplier: Thermo Fisher Scientific
4-Fluorophenylglyoxal hydrate, hydrate 98%
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γ-Cyclodextrine hydrate
Supplier: Thermo Fisher Scientific
γ-Cyclodextrine hydrate
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4-Fluorophenylglyoxal hydrate
Supplier: Apollo Scientific
4-Fluorophenylglyoxal hydrate
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β-Cyclodextrine hydrate
Supplier: Thermo Fisher Scientific
β-Cyclodextrine hydrate
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2'-Deoxyguanosine hydrate
Supplier: Apollo Scientific
2'-Deoxyguanosine hydrate
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Pentafluoropropionaldehyde hydrate
Supplier: Apollo Scientific
Pentafluoropropionaldehyde hydrate
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Azomethine H hydrate
Supplier: Thermo Fisher Scientific
Azomethine H hydrate
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(R)-(-)-Phencyphos hydrate
Supplier: Apollo Scientific
(R)-(-)-Phencyphos hydrate
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Chloral hydrate, GPR RECTAPUR®
Supplier: VWR Chemicals
Chloral hydrate, GPR RECTAPUR®
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β-Cyclodextrine hydrate 99%
Supplier: Thermo Fisher Scientific
β-Cyclodextrine hydrate 99%
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4-Methylphenylglyoxal hydrate 95%
Supplier: Apollo Scientific
4-Methylphenylglyoxal hydrate 95%
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3-Methoxyphenylglyoxal hydrate 96%
Supplier: Apollo Scientific
3-Methoxyphenylglyoxal hydrate 96%
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D-(+)-Melezitose hydrate ≥99%
Supplier: Thermo Fisher Scientific
D-(+)-Melezitose hydrate ≥99%
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Haematoxylin hydrate, (max. 6% H₂O)
Supplier: Thermo Fisher Scientific
Haematoxylin hydrate, (max. 6% H₂O)
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3-Fluorophenylglyoxal hydrate 97%
Supplier: Apollo Scientific
3-Fluorophenylglyoxal hydrate 97%
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Chloral hydrate 98.5%
Supplier: Thermo Fisher Scientific
Chloral hydrate 98.5%
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3-Chlorophenylglyoxal hydrate 95%
Supplier: Apollo Scientific
3-Chlorophenylglyoxal hydrate 95%